Cushing's Syndrome

Cushing’s syndrome is an endocrine disorder that is caused
by the excessive production of cortisol that is synthesized
and released from the zona fasciculata cells of the adrenal
cortex. 
The syndrome is characterized by multiple symptoms such as rapid weight gain with an unusual distribution in the trunk, face and along the collar bone. 
Other symptoms include increased sweating, dilation's of the capillaries, atrophy of the skin, which bruises easily, and females can develop a male facial pattern of hair growth. 
There may also be psychological disorders such as depression and anxiety.

Treatment usually includes drugs such as octreotide, bromocriptine and cyproheptadine modulate the release of ACTH from the pituitary gland, thereby moderating the levels of cortisol in the body.
In some cases if adrenal adenoma is the cause of excess cortisol levels then removing the adenoma is the right treatment option.
After having the adenoma removed the body needs to have cortisol levels stabilized usually Mifepristone is prescribed to stabilize the cortisol levels.
Mifepristone is a cortisol receptor antagonist sometimes used in the treatment of elevated levels of cortisol due to ectopic adrenocorticotrophin (ACTH)-producing tumors. Mifepristone competitively binds glucocorticoid receptors and suppresses the peripheral features of hypercortisolism in Cushing's syndromes.

 Works Cited

Berridge, Michael J. "Signalling Defects and Disease." Cushing's Syndrome (2008): n. pag. Physiology.sdu.edu. Portland Press Limited, 2009. Web. 10 Nov. 2014.

Lin D, Loughlin K. "National Endocrine and Metabolic Diseases Information Service (NEMDIS)." Cushing's Syndrome Page. N.p., 6 Apr. 2012. Web. 10 Nov. 2014.

Scarano, Adam. "What Drugs Lower High Cortisol Levels?" LIVESTRONG.COM. LIVESTRONG.COM, 24 Oct. 2013. Web. 10 Nov. 2014.